After weeks of silence, the Servier Laboratory out of the wood on Sunday, speaking through its Executive Director, Lucy Vincent, who spoke in the Journal du Dimanche.If the manager insists, in the tradition of his boss Jacques Servier, the figures given by the latest study – of 500 to 2,000 dead are estimates and extrapolations, not "confirmed cases" of death after taking the Mediator medication for the first time, leaders from Servier admit – or rather "does not deny – that the treatment was able to" present a real risk for some patients. "
Thus, the figure "shocking" deaths of three advanced during the presentation of the wishes of Jacques Servier last Tuesday was not contested by Lucy Vincent, even though she believes that "if the Mediator has killed three people, c is already too much. "
The report confirmed that the risks Servier
A study by a cardiologist for the Servier Laboratory in 2009 showed a clear link between taking Mediator and heart disease.What Lucy Vincent said that "accountability (to be presented to the Mediator excess risk of developing valvulopathy, Ed) seems likely.
Despite this linkage, Servier has tried to keep this product on the market Afssaps (French Health Authority), Lucy Vincent arguing that "it was natural to ask the question of the benefit-risk knowing that the Mediator was the only drug that can treat some diabetics. The Authority nevertheless considered that the "risk-benefit" was "inadequate". This marked the end of the marketing of the media in November 2009 when he was put on the market in 1976 and 145 million boxes were sold.A decision that "we (the Servier Laboratory, Ed) were never challenged," the director notes in the JDD.
The Mediator as an appetite suppressant
Except that, in addition to case-diabetic diabetologists uses almost the most Mediator since 1998, when he was no longer classified as "top the treatment of diabetes – the Mediator was mainly prescribed as an appetite suppressant by doctors Lucy Vincent up as guilty of misuse: "His only evidence has been diabetes," she quips payday loans.
Asked by lefigaro.fr an obesity expert based in Paris, which he has "never prescribed this drug," says the Mediator did lose a few pounds by eliminating sugar. "It was a psychotropic drug, which acted on the psychological state. Isomeride was the encore, he adds.The Isomeride was another drug amphetamine derivative produced by Servier, withdrawn from sale worldwide in 1997.
Moreover, since 1998, three doctors of the Social Security warned against the indiscriminate use of the Mediator, a product of amphetamine structure then used in a "completely free" for purposes anorectic "while the drug group of amphetamine is strictly controlled since May 1995. "
Blame the weather
"That does not justify it special monitoring" of Mediator, and engages the JDD? This has been done, "retorted Lucy Vincent, with the investigation launched in 1998 Afssaps, which supported his research on the relationship between the Mediator and pulmonary arterial hypertension, yet without dwelling on the valvular . This was done much later, in 2009."We made eye opener in and as soon as possible based on information available to us when they appeared," she says. Thus, Lucy Vincent presents the fault at the time: "Science is moving slowly."
ALSO READ:
"Mediator: Health Insurance in 1998 warned
"Mediator: Nicolas Sarkozy called for" transparency "
"Mediator: an alarming cost to Safely in 1998
"Mediator: an association of 110 complaints
"Mediator: a report confirming the risk of Servier
Xavier Bertrand wants to go fast. He intends, as he promised when taking office at the Ministry of Labour in mid-November, implement all the tools that exist to reduce unemployment in a sustainable manner. He reiterated this weekend in an interview with Sunday newspaper, youth employment is a priority.
"I will review the trade unions and employers before the end of the year, proposals should emerge in early 2011, with new tools and targets," he says. It also welcomes "the social partners' wish to move quickly and (…) lead on youth employment by the end of the first quarter."
Valuing
There is however one caveat: if it finds that "it's a good thing" that trade unions and employers' wish to discuss among themselves the issue of internships or any mobilization of the 1% housing they manage, "he considers that "there are other issues to be addressed" and that "our dual system can be improved in several respects."
"About 7% of young people this type of training and they lead to sustainable employment for a vast majority of them. In Germany they are 17%.I would exceed the 10%, which corresponds to 800,000 more young people, "said the minister.
Among the "many lines of inquiry" that he wants to share with the trade unions and employers on the alternation, the Minister cited the "status" of the apprentice that "must be more rewarding and give it access to rights similar to students in higher education. "
And to increase the number of young companies in alternating, Xavier Bertrand believes that "if sanctions and incentives go hand in hand, we get better results." "Is it fair that a company, including a major undertaking which employs no employees alternately pays the same penalty as that made an effort without reaching the quota? Is it normal that our system of taxation on the subject based only on the sentence? "Asks he.
(With AFP)
ALSO READ:
"Interview CGT / MEDEF: Thibault disappointed
»INFO ON DEMAND – Features the fight against unemployment
Bertrand / Unemployment accompany more
The unions are preparing "after retirement"
"Chérèque wants to negotiate on employment
"The biggest decline since February 2008"
"Social: the threefold mission of Xavier Bertrand
While the station is trying to forget the idea laquelleles train tickets are expensive and reserved for wealthy clients, the Secretary of State for Transport, Thierry Mariani, has said on Europe 1 this Saturday, in favor of increasing ticket prices.
The secretary of state spoke up "quite reasonable" that would take account of inflation and would maintain some rail lines. "I support a balanced position where the user pays according to inflation , an increase entirely reasonable, "he said.
State railways alarming
This increase would occur in parallel with an increase in tolls, which are fees paid by companies to get their trains.
"Do not raise tolls this means that the taxpayer would subsidize (by itself, ie) maintenance, rail lines," said Thierry Mariani. Réseau Ferré de France (RFF), the public manager of the French railways, this week launched a cry of alarm about the situation of French railways, which could partly be dropped for lack of money for their maintenance.
Maintenance cost uninsured
According to RFF, much of the network is threatened with obsolescence in the longer term."The funding for the renewal of the network is not assured in the long term, including one used by the TGV, was worried Alain Sauvant, director of strategy RFF.
While the "full cost" of the rail network, including track maintenance and renewal when they are just too worn-is estimated at about 6.5 billion euros per year, revenues covered only 83 RFF % of this amount.
(With AFP)
ALSO READ: "The SNCF launches price offensive
"Lack of investment threatens the future of the TGV
"Prices have soared since TGV 2002
The Court of Auditors pin RATP and SNCF
Back in Exchange for General Motors succeeded! Three weeks after AIA and its more than 20.51 billion dollars raised in Hong Kong, General Motors announced that its IPO, expected Thursday, will be the largest in U.S. history. And even the world if the over-allotment option is exercised. At the opening of the New York Stock Exchange, the action jumps from 6.82% to 35.25 dollars.
The American manufacturer will offer to sell 478 million shares (against 365 million previously proposed at a price between 26 and 29 dollars), at a price of 33 dollars.Total supply will be $ 20.1 billion or 23.1 billion dollars if the over-allotment option, that is to say, any emissions of additional shares in the event of high demand, are fully exercised , says he.
That General Motors will do better than Visa in 2008, had raised $ 19.7 billion, including over-allotment option. "Raising prices is a sign of a vote of confidence in the company and the action they propose," said Michelle Krebs, an analyst Edmunds.Com.
Unbelievable but true … On the one hand, candidates who have all the trouble to find a job in a market where unemployment is still rife. On the other, companies that fail to find the right profiles for posts yet attractive. The mismatch between supply and demand is in full swing! In a sense, this is good news, notes Hugh Pariot, owner of recruitment firm Expectra just prepare a guide of those trades so-called "tension" (1).
"For two years we only talking about terminations. The identification of occupations under pressure proves that we are moving toward a resumption of the employment market, "he says. Developed to help companies attract these "key people", this guide lists no fewer than 19 profiles.It is not exhaustive but can understand why some skills are missing.
New requirements
First there is the needs arising from the crisis, related to risk management. This is the case of the lawyer in a company – 51% of deals between June 2009 and June 2010 – or even the industrial buyer, which plays a vital role in optimizing costs. A job for which an 'ideal' profile is that of a general engineer with additional training in procurement, usually in business school. Rather rare. And to cap it all, businesses want experienced … With the lessons learned from the crisis, "credit managers, responsible for managing financial risks, are also being wooed."Especially in SMEs, thereby avoiding the use of corporate risk analysis," says Hugh Pariot no fax pay day loan.
Technological changes have created new needs. The "community manager", which aims to create a buzz around a brand, gives pride to young graduates, keen on social networks and trained on the job. The "ICT project manager" is also part of the profiles found. Responsible for conducting an IT project, it is both technician, manager and good communicator. Profile: 37 years + 5 tray, twelve years of experience …
Hugh Pariot explains the posture of firms. "With little visibility into the recovery, they try to clone the current employees." By requesting such an IT expert to have interpersonal skills, "while their job is more technical."Or by requiring an engineer R & D that is specialized in aviation, "then came a profile of the car is perfectly adaptable. In response, the conclusion of the Director of Expectra is simple: "Companies must be willing to take risks, to train new recruits and to assess potential candidates, rather than focusing on skills. As for candidates, their aspirations will not be a surprise for recruiters: they want better missions and attractive salary …
(1) Survey conducted among 7000 professionals.
SERVICE:
»See all offers training
The world's financial leaders are preparing for a crucial passage of arms this weekend in South Korea on the burning issue of exchange rates. At least one month of the G20 summit in Seoul, finance ministers and central bank governors of the twenty largest economies in the world are found in Gyeongju to try to declare a truce in the war raging Exchange since September and threatening the global recovery, according to the World Trade Organization (WTO).
The United States and Europe want to impose on China and emerging countries the principle of a mechanism for regulating the exchange rate."We want countries move towards a single set of standards," warned Timothy Geithner, U.S. Treasury Secretary, before flying to the Land of the Morning Calm-.
Beijing and Seoul in particular are accused of keeping their currencies artificially low to protect their exports, despite the strength of their economies payday loans in one hour. And "today, the competitive devaluation has become a weapon of choice," Justice Joseph Stiglitz, Nobel Prize in economics.
Seoul between two chairs
Smelling the trap, China took the lead last Tuesday, raising for the first time since 2007 interest rates. A decision officially justified by the fight against inflation, but allowing Beijing to deflect criticism that it expects the G20 on 11 November. The South Korean presidency of this summit is not easy.Seoul will play the mediator to ensure the success of "his" summit, while maintaining the lowest its own currency, the won, which threatens the assessment its exports.
Facing Washington and the European Union, Brazil, which was the first country to be alarmed by the "war of currencies" has chosen for its policy of empty chair. His Economy Minister, Guido Mantega and central bank governor, Henrique Meirelles, will remain in Brasilia this weekend for a meeting aimed at containing the outbreak of the real …
This shows the gap between the heavyweights of G20. "An agreement in Gyeongju is unrealistic. There will be frank explanations that will prepare the ground for a compromise between the heads of state in Seoul, predicted Huh Chan-guk, a professor at Chungnam National University.Moreover, a statement urging the G20 to break the cycle of competitive devaluation is already on the table 500 payday loans .
The battle is decisive for Europe, which is affected by the policy of printing money taken by Washington and the downward manipulation of the currencies of emerging countries. The rise of the euro "is an obstacle to our economic recovery," a court counselor Olli Rehn, EU Commissioner for Monetary Affairs. Christine Lagarde, Jean-Claude Trichet and other representatives of the euro area will have to stick together to avoid a "G2" Monetary Beijing-Washington.
ALSO READ:
"A" new phase "in the foreign exchange market
"War of the exchange: The IMF requires cooperation
Why China resists sue the yuan
For the sixth day of strikes and demonstrations held since September against the proposed pension reform, mobilization is not weakening, according to the CGT and CFDT. Both unions felt that 3.5 million number of people in the street in France on Tuesday, as many as 12 October. The Interior Ministry has yet identified 1.1 million people, against 1.23 last Tuesday. Mobilization is slightly down.
At Toulouse and Rennes, participation on an upward trend, and also in Marseille, with figures ranging between 23,000 demonstrators by the police, and 240,000 according to unions. In Paris, the trend is similar to that prevailing at the national level, with 60,000 protesters identified by the Prefecture of Police, against 65,000 on October 12. For the CGT, however, the Parisian protesters numbered 330,000, as in the last movement.
"The reactions of Martine Aubry, and Segolene Royal, present in the procession in Paris:
More info on video itélé.fr
Faced with global figures advanced, Prime Minister François Fillon held on Tuesday before the UMP deputies that the movement "began to falter, but becoming more radical." He was referring to the many excesses that marked the movements of students. Of "slips" under which the President of the CFE-CGC Tuesday called for "a pause to refocus the actions of trade unions" at the start of the parade in Paris.
"The reaction of Bernard Thibault, secretary general of the CGT, the violence:
More info on video itélé.fr
"A call for calm as relayed by Francois Chereque, secretary general of the CFDT:
Between 25 and 30 million of new money
Rumours of a takeover, at least part of Paris Saint-Germain resurfaced. According to Expansion, Sébastien Bazin, representative of Colony Capital have signed an agreement to sell a stake in the club at the Al Thani, Qatar's royal family. The deal would cover 30% stake in the club, valued by Colony by at least 80 million euros. The royal family of Qatar, which has already acquired the Spanish club Malaga this summer for a check for 36 million euros and inject between 25 and 30 million euros in the PSG. The transaction is conditioned on the other hand the award to PSG by the Mayor of Paris from a long lease (lasting between 18 and 99 years under French law) to operate the Parc des Princes.
Colony denies sale
Contacted by L'Expansion, Colony Capital, who has never hidden its intentions to withdraw from the club where the offer is interesting, has categorically denied "having signed an agreement with any investor whether for all or part PSG flexcheck cash advance capital. "The main shareholder of the Paris Club does not, however, denied that discussions have taken place over several months between the two parties. Expansion states and the eventual agreement was signed in early October, days before the Prix de l'Arc de Triomphe, sponsored by the emirate of Qatar. That day, discussions would then take more consistency. If Colony has denied the prospect of obtaining the land lease from the Parc des Princes, very likely because Colony has succeeded in ousting the latest candidate to obtain it, has certainly attracted investors.Because if he gets the lease, the U.S. pension fund may engage in what he wanted from the beginning of his appointment in 2006 to commercially exploit the Parc des Princes in the renovating and landscaping the complex commercial and / or hotel.
Stilettos, boots, ballet slippers … Against all odds, the shoe excites many actors of Internet commerce. The giant Amazon, which had already created a French department on its site a year ago, wants to strike harder. He announced Tuesday the launch of a specific site, javari.fr, dedicated to footwear and accessories. Like Javari River, a tributary of the Amazon River, this subsidiary should feed its growing insolent.
After the books, records and videos in 2000, software and games next year, electronic products in 2005 and in recent years, toys, kitchenware, watches and jewelry, child care, hygiene and beauty, lighting, sports and recreation or other musical instruments, the online bookseller continues its diversification. Cultural products now account for less than half its sales.United States, and since this summer in Germany and Great Britain, Amazon has launched in the grocery store "dry" (rice, pasta, canned …) called one day to arrive in France too. And in his stronghold of Seattle, he is testing the delivery of fresh produce: fruit and vegetables, milk …
In France, its fourth largest market after the United States, Germany and Great Britain, Amazon book guests for two huge warehouses Orleans (56,000 square meters) and Montelimar, just opened.
"Selling shoes like peas"
Amazon could not long remain away from the fashion category booming on the Internet. It starts with the shoes and bags. In France, this market is estimated by the specialist Spartoo to 480 million online, or 6% of total industry sales. But that is another kettle of fish to sell books or iPods.Seasonality, diversity of supply, the logistics (all sizes available) complicate the matter seriously. Amazon began in 2007 with a website dedicated to the United States called Endless. Faced with a relative failure, he chose to redeem last year's leading independent shoe online, Zappos (800 million dollars in sales). Javari and launched in Japan and Great Britain.
In France, too, he approached the two players in the sector, and Cloggs Free Delivery in late 2008. Without success. "Amazon has tried to redeem ourselves, then we take people, they finally launched their site," laughs Stephen Treppoz, president Cloggs (40 million euros in turnover last year). "We do not sell shoes like peas or DVDs.Amazon is very good for selling certain types of products, less good for others, "ridicules Saragaglia Boris, chairman of Spartoo.com (30 million euros in turnover last year). The two "pure players" French, full internationalization, announce an increase in their activity of 100% this year. They expect the giant U.S. firm foot …. In this regard, Javari hits hard with free shipping next day, guaranteed lowest prices and free returns prepaid.
ALSO READ:
"Amazon is undercutting its Kindle tablet face iPad
In China, vehicle manufacturers have engaged in a frantic race to production capacity. Last listing day, the Japanese Nissan, owned 43% by Renault, said Monday it plans to nearly double his own, to be of 670,000 vehicles per year to 1.2 million by 2012. Either a higher target of 200,000 cars to the group had set last May.
Number three in China, behind General Motors and Volkswagen, but to his compatriots Toyota and Honda, the third largest Nippon Account systematically increased "capacity" so as to not only maintain our market share, but also to try the increase, "said Carlos Ghosn, CEO of Nissan and Renault. His ambition: to rise from 6% currently to 10% eventually.The German Volkswagen has also doubled in size to produce 3 million cars in 2013-2014.
Became the biggest car market in the world last year with 13.6 million vehicles, China has been of Eldorado. This year, sales could rise by 20%, exceeding 16 million copies. After a slowdown in the spring and early summer, they jumped 56% in August.
In recent months, Nissan has not hidden its size in China no longer allowed him to keep pace with the market. First step, Monday inaugurated its first plant of 4 × 4, in Zhengzhou, in central Somalia. It is a joint venture with its local partner Dongfeng, with an annual capacity of 180,000 cars.The group plans to expand alongside two other sites in the country.
Renault Nissan could join in China
Carlos Ghosn confirmed that Renault still absent from this market, did not intend to start immediately its own production site in China. But the French could reach in time the joint venture with Dongfeng Nissan, "he added.
Nissan, Renault, wants to become the world's leading electric car, also fueled strong ambitions in this field in Asia. "The electric car has a great future in China," Ghosn hammered. The Chinese government has in effect set a target to win the next ten years as the leader in this technology.He has been announced before it would launch a five-city pilot program to buy premium "clean" vehicles, which could go up to about 7200 euros for the acquisition of an electric car.
Only problem, the country's government is working on a plan intended to define the modalities of transfer of technology to foreign companies wishing to produce hybrid and electric vehicles in China. A preliminary draft, making it obligatory transfer of technology's most strategic, has raised concerns among builders.
But Nissan is already in talks with Dongfeng to transfer its technology for electric cars in China, according to the agency Dow Jones. Nissan and Dongfeng Electric Leaf occur together on site. "There is no limit to the technology that we bring in China," simply stated Carlos Ghosn.
ALSO READ:
"China: Nissan launches new brand
Comments Off